ResLit - Antimicrobial Resistance Gene & Mutation Database

GenefbiA

non-essential gene involved in activation of delamanid and pretomanid

Protein ChangeD49Y

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Delamanid
Papers: 1

Paper Information1

Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.

PMID 32361756 · 2020

At least 12-fold increase in delamanid MIC

Mutation Information

fbiA: p.D49Y

Protein Change: D49Y
Confers Resistance To: Delamanid
Source Database: Reslit

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