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Browse Mutations nfxBE75K

GenenfxB

transcriptional repressor of MexCD-OprJ efflux pump

Protein ChangeE75K

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Ciprofloxacin|Levofloxacin|Amikacin|Aztreonam|Fosfomycin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Low Ciprofloxacin Concentrations Select Multidrug-Resistant Mutants Overproducing Efflux Pumps in Clinical Isolates of Pseudomonas aeruginosa.

PMID 36000896 · 2022

mutation in nfxB leads to overproduction of efflux pumps

Mutation Information

Protein Change: E75K
Organisms: Pseudomonas aeruginosa
Confers Resistance To: Ciprofloxacin|Levofloxacin|Amikacin|Aztreonam|Fosfomycin

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

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Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research