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Browse Mutations acrBG123A

GeneacrB

subunit of the AcrAB-TolC efflux pump

Nucleotide ChangeG123A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Polymyxin
Organisms: E. coli
Papers: 1

Paper Information1

1

Efflux-linked accelerated evolution of antibiotic resistance at a population edge.

PMID 36400010 · 2022

Mutations in acrB contribute to increased efflux and resistance to polymyxin.

Mutation Information

Nucleotide Change: G123A
Organisms: E. coli
Confers Resistance To: Polymyxin
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research