Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Susceptibility Trends of Zoliflodacin against Multidrug-Resistant Neisseria gonorrhoeae Clinical Isolates in Nanjing, China, 2014 to 2018.
Molecular Epidemiology, Antimicrobial Surveillance, and PK/PD Analysis to Guide the Treatment of Neisseria gonorrhoeae Infections.
Mutations in the parC gene contribute to ciprofloxacin resistance.
The antimicrobial resistance landscape of Neisseria gonorrhoeae in New Zealand from November 2018 to March 2019 and the role of sexual orientation in transmission.
Mutations in parC contribute to resistance to ciprofloxacin.
Molecular epidemiology of drug-resistant Neisseria gonorrhoeae in Russia (Current Status, 2015).
Neisseria gonorrhoeae parC conferring resistance to fluoroquinolones; CARD accession: CARD:3003929
In Vitro Activity of Gepotidacin (GSK2140944) against Neisseria gonorrhoeae.
Mutation identified in isolate 12
WGS to predict antibiotic MICs for Neisseria gonorrhoeae.
Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae.
Characterization of a Neisseria gonorrhoeae Ciprofloxacin panel for an antimicrobial resistant Isolate Bank.
Mutation at position 259 (AGT259CGT) leading to S87R in parC
Global concerns, local challenges: the alarming spread of FC428-related gonococcal strains in Nanchang City, 2021.
single nucleotide polymorphism
Correlation of in vitro susceptibilities to newer quinolones of naturally occurring quinolone-resistant Neisseria gonorrhoeae strains with changes in GyrA and ParC.
Detection of gyrA and parC mutations associated with ciprofloxacin resistance in Neisseria gonorrhoeae by use of oligonucleotide biochip technology.
High prevalence of mutations in quinolone-resistance-determining regions and mtrR loci in polyclonal Neisseria gonorrhoeae isolates at a tertiary hospital in Southern Taiwan.
Mutation in parC was associated with ciprofloxacin resistance.
Molecular characterization of a ceftriaxone-resistant Neisseria gonorrhoeae strain found in Switzerland: a case report.
Hydrogel Droplet Microarray for Genotyping Antimicrobial Resistance Determinants in Neisseria gonorrhoeae Isolates.
Neisseria gonorrhoeae FC428 Subclone, Vietnam, 2019-2020.
associated with ciprofloxacin resistance
Susceptibility of Neisseria gonorrhoeae to Zoliflodacin and Quinolones in Hyogo Prefecture, Japan.
associated with high non-susceptibility to quinolones
Summary and Trends of the Russian Gonococcal Antimicrobial Surveillance Programme, 2005 to 2016.
Temporal evolution of antimicrobial resistance among Neisseria gonorrhoeae clinical isolates in the most populated South American Metropolitan Region.
Meningococcal Quinolone Resistance Originated from Several Commensal Neisseria Species.
Mutations in ParC, such as D86N, S87I, S87R, and E91G, contribute to quinolone resistance in N. meningitidis.
Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution.
Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018.
The isolate had the S87R mutation in parC, reducing quinolone binding to topoisomerase IV.
Whole-Genome Sequencing of Russian Neisseria Gonorrhoeae Isolates Related to ST 1407 Genogroup.
Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018.
causes high-level resistance to ciprofloxacin
Antimicrobial resistance prediction and phylogenetic analysis of Neisseria gonorrhoeae isolates using the Oxford Nanopore MinION sequencer.
Mutations in parC contribute to resistance to ciprofloxacin.
Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.
Identification of Internationally Disseminated Ceftriaxone-Resistant Neisseria gonorrhoeae Strain FC428, China
ParC3 variant
Whole genome analysis and antimicrobial resistance of Neisseria gonorrhoeae isolates from Ghana.
Mutations in parC were associated with fluoroquinolone resistance.
Two cases of extensively drug-resistant (XDR) Neisseria gonorrhoeae infection combining ceftriaxone-resistance and high-level azithromycin resistance, France, November 2022 and May 2023.
Outbreak of Sexually Transmitted Nongroupable Neisseria meningitidis-Associated Urethritis, Vietnam.
Mutation at S87R in parC contributes to ciprofloxacin resistance.
Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from India, Pakistan and Bhutan in 2007-2011.
Mutations in the parC gene contribute to resistance to ciprofloxacin.
Genomic epidemiology and antimicrobial resistance of Neisseria gonorrhoeae in New Zealand.
Whole-genome sequencing reveals transmission of gonococcal antibiotic resistance among men who have sex with men: an observational study.
Cephalosporin-Resistant Neisseria gonorrhoeae Clone, China
Genomic Analysis Reveals Antibiotic-Susceptible Clones and Emerging Resistance in Neisseria gonorrhoeae in Saskatchewan, Canada.
Horizontal Gene Transfer of Fluoroquinolone Resistance-Conferring Genes From Commensal Neisseria to Neisseria gonorrhoeae: A Global Phylogenetic Analysis of 20,047 Isolates.
Substitutions S87R, D86N, and E91G in parC were associated with resistance to ciprofloxacin.
The novel 2024 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations and superseded WHO N. gonorrhoeae reference strains-phenotypic, genetic and reference genome characterization.
carried mutations leading to fluoroquinolone resistance
Emergence of Carbapenem-resistant Clinical Isolates of Providencia Species.
Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates.
parC
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