ResLit - Antimicrobial Resistance Gene & Mutation Database

GenefolA

Protein ChangeL135F

Nucleotide ChangeG407C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Trimethoprim
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

Holistic understanding of trimethoprim resistance in Streptococcus pneumoniae using an integrative approach of genome-wide association study, resistance reconstruction, and machine learning.

PMID 39120145 · 2024

Mutations in intergenic region upstream of sulABCD operon lead to increased expression of sulA

Mutation Information

folA: p.L135F / c.G407C

Protein Change: L135F
Nucleotide Change: G407C
Organisms

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Mutation Information