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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations gyrAA196E

GenegyrA

Protein ChangeA196E

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: DNA gyrase subunit A GyrA, Target modification
Resistance To: QUINOLONE, Nalidixic acid,Ciprofloxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.

PMID 14506034 · 2003

gyrA

Unknown phenotype if A196E occurs alone. Nalidixic acid and ciprofloxacin resistance when associated with other gyrA mutations

Mutation Information

Protein Change: A196E
Organisms: Escherichia coli
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

QUINOLONENalidixic acid,Ciprofloxacin

Effect on Function

DNA gyrase subunit A GyrA; Target modification

Source Database

Reference Gene CatalogResFinder Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research