ResLit - Antimicrobial Resistance Gene & Mutation Database

Generrs

ribosomal RNA small subunit

Nucleotide Changeg1064a

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: Spectinomycin
Organisms: Escherichia coli
Papers: 1

Paper Information1

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation.

PMID 8127669 · 1994

Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to spectinomycin; CARD accession: CARD:3003376

Mutation Information

rrs: c.g1064a

Nucleotide Change: g1064a
Organisms: Escherichia coli
Confers Resistance To

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Mutation Information