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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations ompFG141D

GeneompF

outer membrane porin protein

Protein ChangeG141D

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: outer membrane protein F OmpF, single resistance variant
Resistance To: CEPHALOSPORIN, Beta-lactams
Organisms: Escherichia coli
Papers: 2

Paper Information2

1

The marketplace should not decide who survives. Interview by Emily Friedman.

PMID 2807242 · 1989

ompF

Mutation Information

Protein Change: G141D
Organisms: Escherichia coli
Confers Resistance To: CEPHALOSPORIN

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

outer membrane protein F OmpF

Source Database

Reference Gene Catalog

2

Substitutions in the eyelet region disrupt cefepime diffusion through the Escherichia coli OmpF channel.

PMID 10639355 · 2000

ompF

Escherichia coli ompF with mutation conferring resistance to beta-lactam antibiotics; CARD accession: CARD:3003390

Mutation Information

Protein Change: G141D
Organisms: Escherichia coli
Confers Resistance To: CEPHALOSPORINBeta-lactams
Effect on Function: outer membrane protein F OmpF; single resistance variant
Source Database: Reference Gene CatalogCard Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research