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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations clpC1G258V

ATP-dependent ATPase

Protein ChangeG258V

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: Pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

PMID 30337678 · 2018

Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide; CARD accession: CARD:3004957

Mutation Information

Protein Change: G258V
Organisms: Mycobacterium tuberculosis
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Pyrazinamide

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research