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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations murAD117C

GenemurA

antibiotic-resistant murA transferase

Protein ChangeD117C

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: Fosfomycin
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosis.

PMID 10589726 · 1999

Mycobacterium tuberculosis intrinsic murA conferring resistance to fosfomycin; CARD accession: CARD:3003784

Mutation Information

Protein Change: D117C
Organisms: Mycobacterium tuberculosis
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Fosfomycin

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research