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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations marRI49S

GenemarR

global regulator

Protein ChangeI49S

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: transcriptional regulator MarR, single resistance variant
Resistance To: AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE, Multiple antibiotics
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Overexpression of the marA or soxS regulatory gene in clinical topoisomerase mutants of Escherichia coli.

PMID 9687412 · 1998

Escherichia coli AcrAB-TolC with MarR mutations conferring resistance to ciprofloxacin and tetracycline; CARD accession: CARD:3003378

Mutation Information

Protein Change: I49S
Organisms: Escherichia coli
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Multiple antibiotics

Effect on Function

single resistance variant

Source Database

Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research