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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations marRR77L

GenemarR

global regulator

Protein ChangeR77L

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: transcriptional regulator MarR, single resistance variant
Resistance To: AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE, Multiple antibiotics
Organisms: Escherichia coli
Papers: 2

Paper Information2

1

Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli.

PMID 8383113 · 1993

marR

Mutation Information

Protein Change: R77L
Organisms: Escherichia coli
Confers Resistance To: AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

transcriptional regulator MarR

Source Database

Reference Gene Catalog

2

Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding.

PMID 10760140 · 2000

Escherichia coli AcrAB-TolC with MarR mutations conferring resistance to ciprofloxacin and tetracycline; CARD accession: CARD:3003378

Mutation Information

Protein Change: R77L
Organisms: Escherichia coli
Confers Resistance To: Multiple antibiotics
Effect on Function: single resistance variant
Source Database: Card Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research