ResLit - Antimicrobial Resistance Gene & Mutation Database

GenesoxR

ATP-binding cassette (ABC) antibiotic efflux pump;major facilitator superfamily (MFS) antibiotic efflux pump;resistance-nodulation-cell division (RND) antibiotic efflux pump

Protein ChangeS128del

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: redox-sensitive transcriptional activator SoxR
Resistance To: AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE
Organisms: Escherichia coli
Papers: 1

Paper Information1

Constitutive soxR mutations contribute to multiple-antibiotic resistance in clinical Escherichia coli isolates.

PMID 15980345 · 2005

soxR

Mutation Information

soxR: p.S128del

Protein Change: S128del
Organisms: Escherichia coli
Confers Resistance To: AMPICILLIN/CHLORAMPHENICOL/QUINOLONE/RIFAMPIN/TETRACYCLINE

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Mutation Information