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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rpoBS558F

GenerpoB

Protein ChangeS558F

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: DNA-directed RNA polymerase subunit beta RpoB
Resistance To: RIFAMPIN
Organisms: Neisseria meningitidis
Papers: 2

Paper Information2

1

Multicenter study for defining the breakpoint for rifampin resistance in Neisseria meningitidis by rpoB sequencing.

PMID 20606072 · 2010

rpoB

Mutation Information

Protein Change: S558F
Organisms: Neisseria meningitidis
Confers Resistance To: RIFAMPIN

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

DNA-directed RNA polymerase subunit beta RpoB

Source Database

Reference Gene Catalog

2

Molecular characterization of rifampin-resistant Neisseria meningitidis.

PMID 8092823 · 1994

rpoB

Mutation Information

Protein Change: S558F
Organisms: Neisseria meningitidis
Confers Resistance To: RIFAMPIN
Effect on Function: DNA-directed RNA polymerase subunit beta RpoB
Source Database: Reference Gene Catalog

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research