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Browse Mutations acrBH338A

GeneacrB

subunit of the AcrAB-TolC efflux pump

Protein ChangeH338A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: resistance to fusidic acid and β-lactams
Resistance To: Fusidic acid
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB.

PMID 27982032 · 2016

Mutations in TM2 affect efflux of fusidic acid and beta-lactams

Mutation Information

Protein Change: H338A
Organisms: Escherichia coli
Confers Resistance To: Fusidic acid

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

resistance to fusidic acid and β-lactams

Source Database

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research