Unknown

S81Y

Gene: gyrA
Curation StatusNot Validated

Overview

Resistance To
gemifloxacin|trovafloxacin|sparfloxacin|ciprofloxacin
Organisms
Streptococcus pneumoniae
Paper
1
Paper Information1
1

Activity of gemifloxacin against quinolone-resistant Streptococcus pneumoniae strains in vitro and in a mouse pneumonia model.

PMID 15728901 · 2005

Mutations in gyrA were associated with increased resistance to fluoroquinolones.

Mutation Information

Gene Name
gyrA
Protein Change
S81Y

Confers Resistance To

gemifloxacin|trovafloxacin|sparfloxacin|ciprofloxacin

Organisms Observed In

Streptococcus pneumoniae
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