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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rpoDE98K

GenerpoD

Protein ChangeE98K

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: RNA polymerase sigma factor RpoD
Resistance To: Ceftriaxone, CEPHALOSPORIN
Organisms: Neisseria gonorrhoeae
Papers: 1

Paper Information1

1

RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates.

PMID 32011233 · 2020

The rpoD E98K mutation was identified in CRO RS isolates and confirmed to confer resistance through transformation experiments.

rpoD

Mutation Information

Protein Change: E98K
Organisms: Neisseria gonorrhoeae
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

CeftriaxoneCEPHALOSPORIN

Effect on Function

RNA polymerase sigma factor RpoD

Source Database

ReslitReference Gene Catalog

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research