Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Adding Insult to Injury: Mechanistic Basis for How AmpC Mutations Allow Pseudomonas aeruginosa To Accelerate Cephalosporin Hydrolysis and Evade Avibactam.
Mutations in ampC lead to reduced avibactam inhibition and increased resistance to ceftolozane and ceftazidime.
Restoring ceftolozane susceptibility: a role for diazabicyclooctane β-lactamase inhibitors?
Mutations in ampC were the primary mechanism of TOL-TAZ resistance.
Biochemical Insights into Imipenem Collateral Susceptibility Driven by ampC Mutations Conferring Ceftolozane/Tazobactam Resistance in Pseudomonas aeruginosa.
Mutations in the Ω-loop of ampC lead to increased resistance to ceftolozane/tazobactam and decreased resistance to imipenem.
Monitoring of Pseudomonas aeruginosa mutational resistome dynamics using an enrichment panel for direct sequencing of clinical samples.
Mutation detected in a 1:100 mixture of wild-type and mutant isolates.
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