ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemrcB

penicillin-binding protein

Protein ChangeS459A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Colistin
Organisms: Acinetobacter baumannii
Papers: 1

Paper Information1

Septal Class A Penicillin-Binding Protein Activity and ld-Transpeptidases Mediate Selection of Colistin-Resistant Lipooligosaccharide-Deficient Acinetobacter baumannii.

PMID 33402533 · 2021

Mutation in the dd-tpase domain of mrcB leads to septation defects and supports colistin resistance.

Mutation Information

mrcB: p.S459A

Protein Change: S459A
Organisms: Acinetobacter baumannii
Confers Resistance To: Colistin
Source Database: Reslit

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