ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeG547W

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: associated with the overexpression of an OmpA-like protein (pdsO), which may help maintain membrane integrity and increase resistance to beta-lactam antibiotics
Resistance To: Beta-lactam
Organisms: Shewanella algae
Papers: 1

Paper Information1

Emergence of carbapenem resistance in persistent Shewanella algae bacteremia: the role of pdsS G547W mutation in adaptive subpopulation dynamics.

PMID 39568026 · 2024

The G547W mutation in pdsS is associated with the overexpression of pdsO, which may help maintain membrane integrity and increase resistance to beta-lactam antibiotics.

Mutation Information

pdsS: p.G547W

Protein Change: G547W
Organisms: Shewanella algae
Confers Resistance To

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Mutation Information