Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
blaADC-7 beta-lactamase | G222D | - | increased resistance to ceftazidime and cefepime | Acinetobacter baumannii, Escherichia coli | ceftazidimecefepime | Reslit | Candidate |
blaC beta-lactamase | A49G | - | - | Mycobacterium tuberculosis | amoxicillincefotaxime | Reslit | Candidate |
blaC β-lactamase | G132N | - | - | - | carbapenems | Reslit | Candidate |
blaC β-lactamase | G207* | - | abolish BlaC function | Mycobacterium tuberculosis | penicillincephalosporinscarbapenems | Reslit | Candidate |
blaC β-lactamase | I105F | - | enhanced catalytic efficiency and stability | Escherichia coli, Mycobacterium smegmatis | ampicillin | Reslit | Candidate |
blaC class A β-lactamase | I105G | - | - | Escherichia coli | clavulanic acidavibactam | Reslit | Candidate |
blaC class A β-lactamase | I105R | - | - | Escherichia coli | clavulanic acidavibactam | Reslit | Candidate |
blaC β-lactamase | I105T | - | enhanced catalytic efficiency and stability | Escherichia coli, Mycobacterium smegmatis | ampicillin | Reslit | Candidate |
| N346D | - | reduced capability to convey antibiotic resistance | Enterobacter cloacae | ampicillincephalothin | Reslit | Candidate | |
blaC β-lactamase | P107T | - | reduced ability to degrade either antibiotic | Escherichia coli | ampicillincarbenicillin | Reslit | Candidate |
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