Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoD RNA polymerase sigma factor	-	G1331A	-	Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa	imipenem	Reslit	Candidate
rpoD DNA-directed RNA polymerase sigma subunit	A187T	-	-	Staphylococcus aureus	nafcillin	Reslit	Candidate
rpoD DNA-directed RNA polymerase sigma subunit	A194V	-	-	Staphylococcus aureus	nafcillin	Reslit	Candidate
rpoD RNA polymerase sigma factor	A444V	-	-	Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa	imipenem	Reslit	Candidate
rpoD sigma factor 70	D445V	-	increased β-lactam resistance	Escherichia coli, E. coli	amoxicillinampicillincefoxitin+1 more	Reslit	Supported
rpoD	DDDA92del	-	RNA polymerase sigma factor RpoD	Neisseria gonorrhoeae	cephalosporins	Reference Gene Catalog	Established
rpoD RNA polymerase delta subunit	E98K	-	RNA polymerase sigma factor RpoD	Neisseria gonorrhoeae	ceftriaxonecephalosporins	Reference Gene CatalogReslit	Confirmed
rpoD RNA polymerase sigma factor RpoD	I229V	-	-	Neisseria gonorrhoeae	ceftriaxone	Reslit	Candidate
rpoD sigma factor	T119I	-	-	Salmonella Typhimurium	triclosan	Reslit	Candidate
rpoD sigma factor	T539G	-	-	Escherichia coli	aztreonamclavulanic acid	Reslit	Candidate