Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
Rv0678 transcription repressor for efflux pump MmpL5 | L122P | - | - | - | clofaziminebedaquiline | Reslit | Supported |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | L125P | - | - | - | bedaquilineclofazimine | Reslit | Candidate |
Rv0678 hypothetical protein | L136P | - | - | Mycobacterium tuberculosis | cfzbedaquilineclofazimine | Reslit | Supported |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | L139P | - | - | - | bedaquilineclofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | L142P | - | - | - | bedaquilineclofazimine | Reslit | Candidate |
Rv0678 repressor protein that regulates mmpS5/mmpL5 efflux pump gene expression | L154P | - | - | - | bedaquilineclofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | L155P | - | - | - | bedaquilineclofazimine | Reslit | Candidate |
| L32S | - | single resistance variant | Mycobacterium tuberculosis | bedaquilineclofazimine | Card Database | Established | |
Rv0678 MmpR transcriptional repressor | L40F | - | - | Mycobacterium tuberculosis | bedaquiline | Reslit | Candidate |
Rv0678 Membrane-bound transcriptional regulator | L40S | - | - | bedaquilineclofazimine | Reslit | Candidate |
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