Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
Rv0678 Membrane-bound transcriptional regulator | P48L | - | - | bedaquilineclofazimine | Reslit | Candidate | |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | Q115* | - | nonsense mutation | Mycobacterium tuberculosis | bedaquilineclofazimine | Card DatabaseReslit | Confirmed |
Rv0678 Membrane-bound transcriptional regulator | Q115P | - | - | bedaquilineclofazimine | Reslit | Candidate | |
| Q22* | - | nonsense mutation | Mycobacterium tuberculosis | bedaquilineclofazimine | Card Database | Established | |
Rv0678 mmpR5 repressor protein | Q22L | - | - | Mycobacterium tuberculosis | bedaquilineclofazimine | Reslit | Candidate |
Rv0678 negative regulator of the MmpS5-MmpL5 efflux pump | Q22P | - | - | Mycobacterium tuberculosis | clofaziminebedaquiline | Reslit | Supported |
Rv0678 unknown | Q31R | - | - | - | bedaquilineclofazimine | Reslit | Candidate |
Rv0678 transcription repressor for efflux pump MmpL5 | Q51R | - | - | - | clofaziminebedaquiline | Reslit | Candidate |
| Q76* | - | nonsense mutation | Mycobacterium tuberculosis | bedaquilineclofazimine | Card Database | Established | |
| R107C | - | - | Mycobacterium tuberculosis | bedaquiline | Reslit | Candidate |
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