Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
eis Eis protein | C14T | - | - | - | kanamycinamikacincapreomycin | Reslit | Candidate |
eis aminoglycoside resistance enzyme | D26A | - | modestly reduced the binding affinity of Eis to KAN | Mycobacterium tuberculosis | kanamycin | Reslit | Candidate |
eis aminoglycoside resistance enzyme | F84A | - | modestly increased affinity of Eis to KAN | Mycobacterium tuberculosis | kanamycin | Reslit | Candidate |
eis Eis protein | G10A | - | - | - | kanamycinamikacincapreomycin | Reslit | Candidate |
| G11R | - | - | kanamycinamikacin | Reslit | Candidate | ||
eis Eis protein | G37T | - | - | - | kanamycinamikacincapreomycin | Reslit | Candidate |
eis enhanced interspersed element | P86L | - | - | Mycobacterium tuberculosis | capreomycin | Reslit | Candidate |
| R12Q | - | - | - | kanamycin | Reslit | Candidate | |
eis aminoglycoside resistance enzyme | R37G | - | insignificantly altered KAN acetylation | Mycobacterium tuberculosis | kanamycin | Reslit | Candidate |
eis aminoglycoside resistance enzyme | S83G | - | statistically significantly increased (2-fold) the catalytic efficiency of the enzyme | Mycobacterium tuberculosis | kanamycin | Reslit | Candidate |
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