Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
Rv0678 transcription repressor for efflux pump MmpL5 | T33N | - | - | - | clofazimine | Reslit | Candidate |
Rv0678 MmpR transcriptional repressor | T91P | - | - | Mycobacterium tuberculosis | bedaquiline | Reslit | Candidate |
Rv0678 hypothetical protein | V152A | - | - | Mycobacterium tuberculosis | bedaquiline | Reslit | Candidate |
Rv0678 repressor protein that regulates mmpS5/mmpL5 efflux pump gene expression | V1A | - | - | - | bedaquilineclofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor regulating the efflux pump MmpS5-MmpL5 | V1V | - | - | bedaquilineclofazimine | Reslit | Candidate | |
Rv0678 transcription repressor for efflux pump MmpL5 | V20F | - | - | - | clofazimine | Reslit | Candidate |
| W42* | - | nonsense mutation | Mycobacterium tuberculosis | bedaquiline | Card Database | Established | |
Rv0678 Membrane-bound transcriptional regulator | W42R | - | - | bedaquilineclofazimine | Reslit | Candidate | |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | Y145* | - | nonsense mutation | Mycobacterium tuberculosis | bedaquilineclofazimine | Card DatabaseReslit | Confirmed |
| Y157* | - | nonsense mutation | Mycobacterium tuberculosis | bedaquiline | Card Database | Established |
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