Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampD peptidoglycan hydrolase	G121E	-	-	-	meropenemceftazidime	Reslit	Candidate
ampD	G148A	-	-	Pseudomonas aeruginosa	imipenemmeropenemceftazidime avibactam	Reslit	Candidate
ampD peptidoglycan hydrolase	G169C	-	-	-	fluoroquinolones	Reslit	Candidate
ampD N-acetyl-anhydromuramyl-L-alanine-amidase	H157Y	-	increased basal ampC expression, 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	Pseudomonas aeruginosa	ceftolozane tazobactamimipenemceftazidime+2 more	Reference Gene CatalogReslit	Confirmed
ampD	H36R	-	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	Pseudomonas aeruginosa	cephalosporins	Reference Gene Catalog	Established
ampD	H68Y	-	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	Burkholderia cenocepacia	cephalosporins	Reference Gene Catalog	Established
ampD	H74P	-	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	Burkholderia cenocepacia	cephalosporins	Reference Gene Catalog	Established
ampD regulatory protein involved in AmpC β-lactamase expression	H75Y	C223T	-	-	cefotaximeceftazidimecefepime	Reslit	Candidate
ampD	H77Y	-	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	Pseudomonas aeruginosa	cephalosporins	Reference Gene Catalog	Established
ampD	I113S	-	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	Enterobacter cloacae	aztreonam avibactam	Reference Gene Catalog	Established