Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pbp2b penicillin-binding protein | S480A | - | - | - | cefotaxime | Reslit | Candidate |
pbp2b penicillin-binding protein | S664A | - | - | - | cefotaxime | Reslit | Candidate |
pbp2b penicillin-binding protein 2b | T338A | - | - | Streptococcus pneumoniae | penicillin | Reslit | Candidate |
pbp2b penicillin-binding protein 2B | T402I | - | - | Streptococcus uberis | penicillin | Reslit | Candidate |
pbp2b penicillin-binding protein | T426K | - | - | - | cefotaxime | Reslit | Candidate |
pbp2b penicillin-binding protein 2B | T445A | - | single resistance variant | Streptococcus pneumoniae | amoxicillinpenicillinampicillin+2 more | Card DatabaseReslit | Confirmed |
pbp2b penicillin-binding protein 2B | T446A | reduced affinity for β-lactams | Streptococcus mitis, Streptococcus pneumoniae | beta lactamspenicillinpiperacillin+3 more | Reslit | Supported | |
pbp2b penicillin-binding protein | T450A | - | - | Streptococcus gordonii | penicillin | Reslit | Candidate |
pbp2b penicillin-binding protein 2B | T451A | - | resistance | Streptococcus pneumoniae, Streptococcus mitis/oralis | penicillinmeropenem | Reslit | Supported |
| T488A | - | single resistance variant | Streptococcus pneumoniae | amoxicillin | Card Database | Established |
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