Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrA two-component system response regulator	P102H	-	constitutive activation	Acinetobacter baumannii	colistinpolymyxin bpolymyxins	Reslit	Supported
pmrA response regulator	P102R	C306G	altered phosphorylation, mutated pmrA gene leads to increased colistin resistance	Acinetobacter baumannii	colistin	Reslit	Supported
pmrA transmembrane protein	R118F	-	-	E. coli	colistin	Reslit	Candidate
pmrA Two-component system response regulator	R138H	-	-	Escherichia coli	colistin	Reslit	Candidate
pmrA transmembrane protein	R139P	-	-	E. coli	colistin	Reslit	Candidate
pmrA response regulator	R81C	-	two-component system response regulator PmrA	Salmonella enterica	polymyxin bcolistin	Reference Gene CatalogReslit	Confirmed
pmrA response regulator	R81H	-	confirmed by complementation experiments, two-component system response regulator PmrA	Salmonella enterica, Escherichia coli	polymyxin bcolistinpolymyxins	Reference Gene CatalogReslit	Confirmed
pmrA two-component system transcriptional regulator	R81S	-	Target modification	E. coli, Escherichia coli	colistin	ResFinder DatabaseReslit	Confirmed
pmrA two-component system sensor kinase	S144G	-	affects protein function	E. coli	colistin	Reslit	Candidate
pmrA transmembrane protein	S29G	-	-	E. coli, Escherichia coli	colistin	Reslit	Supported