Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pmrB two-component sensor kinase | G151D | - | - | Escherichia coli | colistin | Reslit | Candidate |
pmrB sensor kinase | G188D | - | gain-of-function, alteration of the HAMP domain, two-component system sensor histidine kinase PmrB | Pseudomonas aeruginosa | colistinpolymyxin b | Reference Gene CatalogReslit | Confirmed |
pmrB two-component system | G188S | - | alteration of the HAMP domain | Pseudomonas aeruginosa | colistin | Reslit | Candidate |
pmrB two-component system sensor kinase | G19R | - | - | Escherichia coli | colistin | Reslit | Candidate |
pmrB two-component system response regulator | G206D | - | gain-of-function, two-component system sensor histidine kinase PmrB | Escherichia coli, Salmonella spp. | colistin | Reference Gene CatalogReslit | Confirmed |
| G206E | - | two-component system sensor histidine kinase PmrB | Salmonella enterica | colistin | Reference Gene Catalog | Established | |
pmrB histidine kinase | G206R | - | Target modification, two-component system sensor histidine kinase PmrB | Salmonella enterica | polymyxin bcolistin | Reference Gene CatalogResFinder DatabaseReslit | Confirmed |
pmrB histidine kinase | G206W | - | Target modification, two-component system sensor histidine kinase PmrB | Salmonella enterica | polymyxin bcolistin | Reference Gene CatalogResFinder DatabaseReslit | Confirmed |
| G207D | - | deleterious | Klebsiella pneumoniae | colistin | Reslit | Candidate | |
pmrB sensor histidine kinase of the PmrAB two-component system | G22E | - | - | Escherichia coli | colistin | Reslit | Candidate |
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