Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pmrB Sensor kinase | L274W | - | - | A. baumannii | colistin | Reslit | Candidate |
pmrB two-component sensor kinase | L323H | - | activating mutation | Pseudomonas aeruginosa | colistin | Reslit | Candidate |
pmrB two-component system sensor kinase | L339C | - | - | Klebsiella pneumoniae | colistin | Reslit | Candidate |
pmrB histidine kinase | L344P | - | enhanced ATP binding affinity and protein stability | Klebsiella pneumoniae | colistin | Reslit | Candidate |
pmrB two-component system histidine kinase | L5S | - | - | Acinetobacter baumannii, Klebsiella pneumoniae | colistin | Reslit | Candidate |
pmrB sensor kinase | L82R | - | two-component system sensor histidine kinase PmrB | Klebsiella pneumoniae | colistinpolymyxins | Reference Gene CatalogReslit | Confirmed |
pmrB two-component system sensor kinase | L9P | - | - | Acinetobacter baumannii | colistin | Reslit | Candidate |
pmrB histidine kinase | M12I | - | - | Acinetobacter baumannii | polymyxin b | Reslit | Candidate |
pmrB two-component system histidine kinase | M145I | - | - | Acinetobacter baumannii | colistin | Reslit | Candidate |
pmrB two-component regulatory system | M145K | - | disruption of pmrB leads to increased susceptibility to colistin | Acinetobacter baumannii | colistin | Reslit | Candidate |
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