Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB two-component system sensor kinase	P170L	C510T	associated with stable resistance, nonsynonymous mutation, two-component system sensor histidine kinase PmrB	Acinetobacter baumannii, Acinetobacter pittii, Acinetobacter seifertii	colistinpolymyxin b	Reference Gene CatalogReslit	Confirmed
pmrB two-component system histidine kinase	P170Q	-	-	Acinetobacter baumannii, Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB putative phosphatase	P170T	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB regulator of outer membrane LPS modification	P175L	-	-	Pseudomonas aeruginosa	colistin	Reslit	Candidate
pmrB two-component system (PmrAB) associated with colistin resistance	P175S	-	-	Pseudomonas aeruginosa	colistin	Reslit	Candidate
pmrB Polymyxin resistant component	P200L	-	-	-	colistin	Reslit	Candidate
pmrB two-component system sensor kinase	P233S	C697T	constitutive activation, associated with stable resistance, two-component system sensor histidine kinase PmrB	Acinetobacter baumannii, A. baumannii	colistinpolymyxins	Reference Gene CatalogReslit	Confirmed
pmrB two-component system sensor kinase	P233T	-	constitutive activation, two-component system sensor histidine kinase PmrB	Acinetobacter baumannii	colistin	Reference Gene CatalogReslit	Confirmed
pmrB two-component regulatory system	P254L	-	-	Pseudomonas aeruginosa	gentamicinstreptomycin	Reslit	Candidate
pmrB PmrB, part of the PmrAB two-component system	P344L	-	-	Klebsiella pneumoniae	colistin	Reslit	Candidate