Fluoroquinolone action against clinical isolates of Mycobacterium tuberculosis: effects of a C-8 methoxyl group on survival in liquid media and in human macrophages.

PMID: 100492841999

Key Findings

Mutation in gyrA at position 90 (A90V) confers resistance to fluoroquinolones.

0gene entries

2mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	A90V	-	-	Mycobacterium tuberculosis, Mycobacterium bovis	Fluoroquinolones	Reslit	-