Carbapenem Derivatives as Potential Inhibitors of Various beta-lactamases, Including Class B Metallo-beta-lactamases.

PMID: 105080311999

Key Findings

The study identifies J-110,441 as a potent inhibitor of various beta-lactamases, including the IMP-1 metallo-beta-lactamase, which is responsible for carbapenem resistance in several bacterial species.

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1gene entry

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaIMP	1	metallo-beta-lactamase	Carbapenem	Pseudomonas aeruginosa Bacteroides fragilis Stenotrophomonas maltophilia Bacillus cereus	Reslit	-

Browse Papers

Carbapenem Derivatives as Potential Inhibitors of Various beta-lactamases, Including Class B Metallo-beta-lactamases.

AMR Genes