Browse Papers

Explore scientific publications on antimicrobial resistance

Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates.

PMID: 111367572001

Key Findings

Detected in one isolate and 5 of 18 RIF-resistant strains with no cluster I mutation

0gene entries

10mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	V176F	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
rpoB	S450W	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-
rpoB	H445C	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-
rpoB	H445D	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-
rpoB	S441Q	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-
rpoB	H445R	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-
rpoB	H445Y	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-
rpoB	R552C	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-
rpoB	L490V	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-
rpoB	E592D	-	single resistance variant	Mycobacterium tuberculosis	Rifampicin	Card Database	-