Plasmid-encoded metallo-beta-lactamase (IMP-6) conferring resistance to carbapenems, especially meropenem.

PMID: 113027932001

Key Findings

The study identifies IMP-6, a plasmid-encoded metallo-beta-lactamase that confers resistance to carbapenems, particularly meropenem, through a single point mutation resulting in an amino acid substitution (Ser-196 to Gly).

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1gene entry
0mutation entries

AMR Genes

Gene NameAllelesEncodesConfers Resistance ToOrganismsDatabaseValidation Status
blaIMP1metallo-beta-lactamase
carbapenems
  • Serratia marcescens
  • Escherichia coli
Reslit
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