Mutational Replacement of Leu-293 in the Class C Enterobacter cloacae P99 beta-lactamase Confers Increased MIC of Cefepime.

PMID: 120191162002

Key Findings

The Leu-293-Pro mutation in the class C Enterobacter cloacae P99 beta-lactamase increases the MIC of cefepime and ceftazidime.

1gene entry

2mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blap99	1	class C beta-lactamase	cefepime	Enterobacter cloacae P99 Escherichia coli JM83	Reslit	-

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
blaP99	-	T294C	-	Escherichia coli, Enterobacter cloacae	cefepime\|ceftazidime	Reslit	-