Role of active efflux in association with target gene mutations in fluoroquinolone resistance in clinical isolates of Vibrio cholerae.

PMID: 121219552002

Key Findings

Mutations in gyrA are associated with fluoroquinolone resistance

0gene entries

5mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83I	-	DNA gyrase subunit A GyrA	Vibrio cholerae	Norfloxacin\|Ciprofloxacin\|Sparfloxacin\|OfloxacinQUINOLONE	ReslitReference Gene Catalog	-
gyrA	Y100D	-	-	Vibrio cholerae	Norfloxacin\|Ciprofloxacin\|Sparfloxacin\|Ofloxacin	Reslit	-
parC	S85L	-	DNA topoisomerase IV subunit A ParC	Vibrio cholerae	Norfloxacin\|Ciprofloxacin\|Sparfloxacin\|OfloxacinQUINOLONE	ReslitReference Gene Catalog	-