Emergence in Klebsiella pneumoniae of a chromosome-encoded SHV beta-lactamase that compromises the efficacy of imipenem.

PMID: 125436882003

Key Findings

The study identifies a novel chromosome-encoded SHV-beta-lactamase, SHV-38, which hydrolyzes imipenem and ceftazidime, compromising the efficacy of these antibiotics against Klebsiella pneumoniae.

View on PubMed

5gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaSHV	1	beta-lactamase	ImipenemCeftazidimeAZTREONAMTICARCILLINCEPHALOSPORINAMOXICILLINCEFEPIMEAMPICILLINCEFOTAXIME+3 more	Klebsiella pneumoniae Escherichia coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Browse Papers

Emergence in Klebsiella pneumoniae of a chromosome-encoded SHV beta-lactamase that compromises the efficacy of imipenem.

AMR Genes