High-level resistance to ceftazidime conferred by a novel enzyme, CTX-M-32, derived from CTX-M-1 through a single Asp240-Gly substitution.

PMID: 151552422004Spain

Key Findings

The study identifies a novel CTX-M-32 beta-lactamase, which confers high-level resistance to ceftazidime through a single Asp240-Gly substitution in the CTX-M-1 enzyme.

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5gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaCTX-M	1	beta-lactamase	CeftazidimeAZTREONAMTICARCILLINCEPHALOSPORINAMOXICILLINCEFEPIMEAMPICILLINCEFOTAXIMECEFTAZIDIME+2 more	Escherichia coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

Browse Papers

High-level resistance to ceftazidime conferred by a novel enzyme, CTX-M-32, derived from CTX-M-1 through a single Asp240-Gly substitution.

AMR Genes