Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center.

PMID: 155618582004New York

Key Findings

The study identifies a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, produced by carbapenem-resistant Klebsiella pneumoniae isolates. The enzyme was encoded on a 75-kb plasmid and conferred resistance to carbapenems, cephalosporins, and other beta-lactam antibiotics.

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4gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaKPC	1	carbapenem-hydrolyzing beta-lactamase	CarbapenemAZTREONAMMEROPENEMTICARCILLINERTAPENEMAMOXICILLINCEFOXITINIMIPENEMTICARCILLIN+CLAVULANIC ACID+9 more	Klebsiella pneumoniae	Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Browse Papers

Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center.

AMR Genes