Genetic analysis of the beta-lactamases of Mycobacterium tuberculosis and Mycobacterium smegmatis and susceptibility to beta-lactam antibiotics.
PMID: 156992012005
Key Findings
The study identifies and characterizes beta-lactamases blaC, blaS, and a putative cephalosporinase blaE in Mycobacterium tuberculosis and Mycobacterium smegmatis, demonstrating their roles in beta-lactam resistance through increased susceptibility in mutants lacking these genes.
3gene entries
0mutation entries
AMR Genes
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| blaC | 1 | beta-lactamase | beta-lactam antibiotics |
| Reslit | - |
| blaE | 1 | putative cephalosporinase | beta-lactam antibiotics |
| Reslit | - |
| blaS | 1 | beta-lactamase | beta-lactam antibiotics |
| Reslit | - |