New mutations and horizontal transfer of rpoB among Rifampin-Resistant Streptococcus pneumoniae from four Spanish hospitals.

PMID: 159175172005

Key Findings

Mutations in rpoB were identified as the cause of rifampin resistance in Streptococcus pneumoniae.

0gene entries

21mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	-	A547T	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C150A	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C486A	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C486T	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C499A	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C499G	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C499T	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C501T	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C535G	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	C537T	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	G489A	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	G489C	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	G489T	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	G638A	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	T481C	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	T482C	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	T485C	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	T495C	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	T498C	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	T506A	-	Streptococcus pneumoniae	Rifampin	Reslit	-
rpoB	-	T506C	-	Streptococcus pneumoniae	Rifampin	Reslit	-