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Evaluation of a new line probe assay for rapid identification of gyrA mutations in Mycobacterium tuberculosis.

PMID: 159803702005

Key Findings

associated with fluoroquinolone resistance

0gene entries

15mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	A90V	-	-	Mycobacterium tuberculosis	Ofloxacin\|Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Gatifloxacin\|Moxifloxacin	Reslit	-
gyrA	D94A	-	-	Mycobacterium tuberculosis	Ofloxacin\|Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Gatifloxacin\|Moxifloxacin	Reslit	-
gyrA	D94H	-	-	Mycobacterium tuberculosis	Ofloxacin\|Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Gatifloxacin\|Moxifloxacin	Reslit	-
gyrA	S95T	-	-	Mycobacterium tuberculosis	Ofloxacin\|Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Gatifloxacin\|Moxifloxacin	Reslit	-
gyrA	D94G	-	-	Mycobacterium tuberculosis	Ofloxacin\|Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Gatifloxacin\|Moxifloxacin	Reslit	-
gyrA	S91P	-	-	Mycobacterium tuberculosis	Ofloxacin\|Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Gatifloxacin\|Moxifloxacin	Reslit	-
gyrA	D94N	-	-	Mycobacterium tuberculosis	Ofloxacin\|Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Gatifloxacin\|Moxifloxacin	Reslit	-