Importance of the GP dipeptide of the "antiporter motif" and other membrane-embedded proline and glycine residues in tetracycline efflux protein Tet(L).

PMID: 161714052005

Key Findings

Mutations in the GP dipeptide of Motif C and other proline and glycine residues affect tetracycline efflux capacity.

0gene entries

6mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
tet(L)	P156A	-	-	Escherichia coli	Tetracycline	Reslit	-
tet(L)	P156C	-	-	Escherichia coli	Tetracycline	Reslit	-
tet(L)	P156G	-	-	Escherichia coli	Tetracycline	Reslit	-
tet(L)	G155S	-	-	Escherichia coli	Tetracycline	Reslit	-
tet(L)	-	G155A	-	Escherichia coli	Tetracycline	Reslit	-
tet(L)	-	G155C	-	Escherichia coli	Tetracycline	Reslit	-