Molecular genetic and structural modeling studies of Staphylococcus aureus RNA polymerase and the fitness of rifampin resistance genotypes in relation to clinical prevalence.

PMID: 163777012006

Key Findings

Mutations in the rpoB gene were identified as conferring rifampin resistance in Staphylococcus aureus.

0gene entries

8mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	H481N	-	-	Staphylococcus aureus	Rifampin	Reslit	-
rpoB	V850A	-	-	Staphylococcus aureus	Rifampin	Reslit	-
rpoB	H481Y	-	-	Staphylococcus aureus	Rifampin	Reslit	-
rpoB	L466S	-	-	Staphylococcus aureus	Rifampin	Reslit	-
rpoB	S529L	-	-	Staphylococcus aureus	Rifampin	Reslit	-
rpoB	A477D	-	-	Staphylococcus aureus	Rifampin	Reslit	-