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Molecular evolution of beta-lactam-resistant Haemophilus influenzae: 9-year surveillance of penicillin-binding protein 3 mutations in isolates from Japan.

PMID: 168014302006

Key Findings

Mutations in PBP3 contribute to β-lactam resistance in Haemophilus influenzae.

0gene entries

5mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp3	-	A377T	-	Haemophilus influenzae	Ampicillin\|Amoxicillin-clavulanic acid\|Cefotiam\|Cefdinir	Reslit	-
pbp3	-	A526G	-	Haemophilus influenzae	Ampicillin\|Amoxicillin-clavulanic acid\|Cefotiam\|Cefdinir	Reslit	-
pbp3	-	C517A	-	Haemophilus influenzae	Ampicillin\|Amoxicillin-clavulanic acid\|Cefotiam\|Cefdinir	Reslit	-
pbp3	-	T385C	-	Haemophilus influenzae	Ampicillin\|Amoxicillin-clavulanic acid\|Cefotiam\|Cefdinir	Reslit	-
pbp3	-	T389C	-	Haemophilus influenzae	Ampicillin\|Amoxicillin-clavulanic acid\|Cefotiam\|Cefdinir	Reslit	-