The Anti-Methicillin-Resistant Staphylococcus aureus Quinolone WCK 771 Has Potent Activity against Sequentially Selected Mutants, Has a Narrow Mutant Selection Window against Quinolone-Resistant Staphylococcus aureus, and Preferentially Targets DNA Gyrase

PMID: 169400592006

Key Findings

Mutations in gyrA confer resistance to WCK 771 and other quinolones.

0gene entries

1mutation entry

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S81F	-	confers resistance	Staphylococcus aureus	Fluoroquinolones	Reslit	-