Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient.

PMID: 172204122007

Key Findings

The study identifies two new complex mutant TEM enzymes, TEM-151 and TEM-152, which exhibit resistance to ceftazidime and show distinct mutational profiles compared to previously known TEM variants.

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10gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaTEM	2	beta-lactamase	CeftazidimeAZTREONAMTICARCILLINCEPHALOSPORINAMOXICILLINTICARCILLIN+CLAVULANIC ACIDCEFEPIMEAMPICILLIN+CLAVULANIC ACIDAMPICILLIN+6 more	Escherichia coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Browse Papers

Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient.

AMR Genes