Erythromycin Resistance-Conferring Plasmid pRSB105, Isolated from a Sewage Treatment Plant, Harbors a New Macrolide Resistance Determinant, an Integron-Containing Tn402-Like Element, and a Large Region of Unknown Function.

PMID: 172615252007

Key Findings

The study identifies two macrolide resistance genes, mel and mph, on plasmid pRSB105, which confer resistance to erythromycin and azithromycin. The mel gene primarily contributes to erythromycin resistance, while mph contributes to both erythromycin and azithromycin resistance.

View on PubMed

1gene entry

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
mph(A)	1	macrolide-2'-phosphotransferase	ErythromycinAzithromycin	Escherichia coli	Reslit	-

Browse Papers

Erythromycin Resistance-Conferring Plasmid pRSB105, Isolated from a Sewage Treatment Plant, Harbors a New Macrolide Resistance Determinant, an Integron-Containing Tn402-Like Element, and a Large Region of Unknown Function.

AMR Genes